Advanced NMR applications in solving Biology problems

A workshop for postgraduate and Ph.D. students on the potential applications of Nuclear Magnetic Resonance (NMR) in the fields of chemical, biological, pharmaceutical and medical sciences to help solve complex biology problems was conducted on 14 Sep 2019 by SSSIHL Central Research Instruments Facility (CRIF).

The workshop was led by Prof. Ramakrishna Vadrevu, BITS Pilani, Hyderabad. Dr Ashish Arora, CSIR-The Central Drug Research Institute (CDRI), Lucknow and Prof. Siddhartha P Sarma, Indian Institute of Science, Bangalore were the invited speakers.

Students were introduced to various NMR techniques including Basics of Magnetic Resonance, principles of one-dimensional, two-dimensional and three-dimensional NMR spectroscopy, and the like.

Detailed discussions about the potential of NMR, including elucidating the structures of complex biological samples like peptides and proteins along with Protein-Ligand interactions in relation to interactions of drug candidates with the therapeutic targets ensued.

Issues relating to using NMR to solve complex structures of the therapeutic targets by using various 2D and 3D NMR techniques in detail with case studies from the experts’ labs, as well as isolating toxins from venoms of snakes and cone snails were deliberated on.

#SSSIHLResearch #SSSIHLCRIF #SSSIHL